David Moyes brings both Fabianski and Cresswell into the starting line-up for this big European tie.
1. Fabianski, 5. Coufal, 4. Zouma, 15. Mavropanos, 3. Cresswell, 19. Alvarez, 28. Soucek, 10. Paqueta, 14. Kudus, 20. Bowen, 9. Antonio
As we get to the business end of the ties, all is to play for as teams look to put their name in the hat for the quarter-finals.
We have four games kicking off at 5.45pm and the remainder will start at 8pm.
Two British sides will take part in the early kick-offs as both West Ham and Rangers are at home.
Aside from Liverpool, everyone has some work to do make sure they progress to the next round.
It should be another action packed night of European football.