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As Japan grapples with donor shortage, scientists breed first pigs for human organ transplant
A Japanese venture-led team has successfully bred three genetically modified pigs for use in human organ and cell transplants for the first time in Japan, which is struggling with donor shortages, the company said on Tuesday.
But the safety of such cross-species transplant will be investigated with further animal testing for the time being, said the venture called PorMedTec that was launched based on the research of the Meiji University International Institute for Bio-Resource Research.
The team including members from US biotechnology company eGenesis bred the pigs, born on Sunday, using cells supplied by the US company in September that had 10 different genes modified to resist rejection by the human body, PorMedTec said in a release.
Fertilised eggs, produced in October using somatic cell cloning technology to create genetically identical individuals, were transplanted into the uterus of a surrogate mother pig. The three piglets were born by caesarean section.