Fulham XI: Leno, Castagne, Andersen, Bassey, Robinson, Berge, Lukic, Sessegnon, Pereira, Iwobi, Muniz.
Liverpool XI: Kelleher, Jones, Konate, Van Dijk, Robertson, Szoboszlai, Mac Allister, Gravenberch, Salah, Jota, Gakpo.
Brentford XI: Flekken, Ajer, Van den Berg, Collins, Lewis-Potter, Norgaard, Yarmoliuk, Damsgaard, Schade, Mbeumo, Wissa.
Chelsea XI: Sanchez, James, Tosin, Chalobah, Gusto, Caicedo, Dewsbury-Hall, Madueke, Enzo Fernandez, Sancho, Nkunku.
The Saints would be relegated from the Premier League if they lose at Tottenham this afternoon.
If their fate is sealed in Matchweek 31, they would become the first Prem team to be relegated with seven games remaining.
Southampton are also trying to avoid having the lowest-ever points tally in Premier League history, which Derby currently holds with 11 points.
THREE thrilling matches come to you from the capital at 2pm as Brentford take on Chelsea, Liverpool travel to Fulham and Tottenham host Southampton.
Ange Postecoglou is in need of a huge three points with his side currently just two points ahead of Wolves in 17th.
Spurs face a Saints side who are rock bottom with 10 points and are desperate not to break Derby’s unwanted record of 11 points - the least amount of points a team have accumulated in a Prem season.
Elsewhere, Chelsea will be aiming to boost their Champions League aspirations with a win over London rivals Brentford this afternoon.
And league leaders Liverpool can 14 points clear at the top with a triumph over Fulham in the capital.