Early team news
Riccardo Calafiori is likely to start on the bench ahead of his debut.
Fabio Vieira is a doubt for the hosts, who are without Takehiro Tomiyasu and Kieran Tierney due to injuries.
Arsenal’s starting line-up will be much the same as the one deployed last season, with Gabriel Jesus and Kai Havertz competing to start up front.
But Thomas Partey will likely get the nod ahead of Jorginho in midfield.
Elsewhere, O'Neil will be delighted with the news that striker Cunha has shaken off his hamstring issues ahead of this huge opening clash.
New forward signing Jorgen Strand Larsen is set to make his debut after Neto joined Chelsea this week.
Welcome to Arsenal vs Wolves
Arsenal kick-start their Premier League season against Wolves at the Emirates TODAY!
The Gunners know a fast start is vital to putting pressure on defending champs Manchester City - who they play next month in what is a tough opening to the 2024/2025 campaign.
Can they launch a third offensive for the Premier League trophy or will they finish second fiddle again? That's the question on everybody's lips.
Despite a series of club records, including 35 wins in 52 matches, to end the season without a trophy was a bitter pill for Mikel Arteta and co. to swallow.
But there's renewed optimism around the Emirates following Riccardo Calafiori's £42m signing to bolster the side's defensive options.
Wolves, meanwhile, impressed last term by putting together an unlikely challenge for Europe under Gary O’Neil before comfortably finishing mid-table.